Representative before the EPO

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We have observed 81 EP applications Simona Müller-Afraz has served for within the last five+ years. (We consider all applications which have an EP A1 publication dated after December 18, 2012). Please note, that we only count EP applications, in which the name of the patent attorney is explicitly mentioned as representative. These EP applications are:

EP11715194

ARYL - /HETEROARYL - CYCLOHEXENYL - TETRAAZABENZO [E]AZULENES AS VASOPRESSIN ANTAGONISTS

IPC classification:
A61K 31/5517, A61P 9/00, A61P 15/00, A61P 25/00, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP11782588

PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/506, A61P 25/16, C07D 401/14, C07D 403/12, C07D 403/14, C07D 405/14, C07D 413/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
The patent has been granted
EP12706041

1,4 THIAZEPINES/SULFONES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/554, A61P 3/10, A61P 25/16, C07D 417/12, C07D 513/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12709616

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/553, A61P 3/10, A61P 25/28, C07D 267/10, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12713127

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/553, A61P 3/10, A61P 25/28, C07D 413/10, C07D 417/10
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12712669

1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/5355, A61P 1/00, A61P 3/10, A61P 7/02, A61P 9/00, A61P 19/02, A61P 25/28, A61P 29/00, A61P 35/00, C07D 265/08, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12722112

1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/535, A61K 31/5355, A61P 25/28, C07D 265/08, C07D 413/10, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12724116

SPIRO-[1,3]-OXAZINES AND SPIRO-[1,4]-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/537, A61P 25/28, C07D 498/10
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP12725747

[1,3]OXAZINES

IPC classification:
A61K 31/5355, A61P 25/28, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP12725743

HALOGEN-ALKYL-1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/5355, A61P 25/28, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12731448

CYCLOPROPYL-FUSED-1,3-THIAZEPINES AS BACE 1 AND/OR BACE 2 INHIBITORS

IPC classification:
C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12759458

N-(3-(2-AMINO-6,6-DIFLUORO-4,4A,5,6,7,7A-HEXAHYDRO-CYCLOPENTA[E][1,3]OXAZIN-4-YL)-PHENYL)-AMIDES AS BACE1 INHIBITORS

IPC classification:
A61K 31/536, A61P 25/28, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP12766618

BENZOIC ACID DERIVATIVES AS EIF4E INHIBITORS

IPC classification:
A61K 31/425, A61K 31/427, A61K 31/4436, A61K 31/4535, A61K 31/497, A61K 31/506, A61K 31/5377, A61P 35/00, C07D 277/34, C07D 277/38, C07D 417/04, C07D 417/08, C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12753948

PARP INHIBITORS

IPC classification:
A61K 31/167, A61K 31/495, A61P 35/00, C07C 317/44, C07D 237/18
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12761740

OXY-CYCLOHEXYL-4H,6H-5-OXA-2,3,10B-TRIAZA-BENZO[E]AZULENES AS V1A ANTAGONISTS

IPC classification:
A61K 31/553, A61P 9/12, C07D 498/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP12766670

CYCLOHEXYL-4H,6H-5-OXA-2,3,10B-TRIAZA-BENZO[E]AZULENES AS V1A ANTAGONISTS

IPC classification:
A61K 31/553, C07D 498/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP12766655

METHODS FOR THE PREPARATION OF 5-[2-[7-(TRIFLUOROMETHYL)-5-[4-(TRIFLUOROMETHYL)PHENYL]PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]ETHYNYL]-2-PYRIDINAMINE

IPC classification:
C07D 213/73, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP12173720

Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives

IPC classification:
A61K 31/4523, A61P 25/24, C07D 205/04, C07D 207/08, C07D 211/30, C07D 401/06, C07D 401/10, C07D 403/06, C07D 403/14, C07D 405/06, C07D 409/06, C07D 409/14, C07D 417/06, C07D 417/14, C07D 451/02, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12794308

2-(PHENYL OR PYRID-3-YL) AMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

IPC classification:
A61K 31/506, A61P 25/16, C07D 403/12, C07D 405/14, C07D 413/12, C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP12791761

2-PHENYLAMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

IPC classification:
A61K 31/505, A61K 31/506, A61P 25/16, C07D 239/47, C07D 239/48, C07D 401/12, C07D 403/12, C07D 405/12, C07D 405/14, C07D 413/12, C07D 487/04, C07D 491/107, C07D 498/08
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP12797828

FLUORINE-18 AND CARBON-11 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR LRRK2

IPC classification:
A61K 51/04
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12791198

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/506, A61K 31/5377, A61K 31/538, A61K 31/553, A61P 25/16, C07D 401/12, C07D 403/12, C07D 403/14, C07D 405/12, C07D 405/14, C07D 413/12, C07D 413/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP13701072

FLUOROMETHYL-5,6-DIHYDRO-4H-[1,3]OXAZINES

IPC classification:
A61K 31/535, A61K 31/5355, C07D 401/12, C07D 403/12, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP12797826

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/505, C07D 239/42, C07D 239/48
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP13718188

(3,4-DICHLORO-PHENYL)-((S)-3-PROPYL-PYRROLIDIN-3-YL)-METHANONE HYDROCHLORIDE AND MANUFACTURING PROCESSES

IPC classification:
A61K 31/40, A61P 25/22, A61P 25/24, C07D 207/08
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP13718860

PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE

IPC classification:
A61K 31/506, A61P 25/16, C07D 471/04, C07D 487/04, C07D 498/04, C07D 498/20
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13720901

PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/506, A61P 25/16, C07D 403/12, C07D 403/14, C07D 407/14, C07D 413/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13723514

SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF

IPC classification:
A61K 31/444, A61P 25/28, C07D 401/12, C07D 401/14, C07D 405/14, C07D 487/08, C07D 491/107
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13725321

5-AMINO[1,4]THIAZINES AS BACE 1 INHIBITORS

IPC classification:
A61K 31/541, A61P 25/28, C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13729285

PYRROLOPYRIMIDONE AND PYRROLOPYRIDONE INHIBITORS OF TANKYRASE

IPC classification:
A61K 31/519, A61P 35/00, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13726532

AUTOIMMUNE ANTIBODIES

IPC classification:
A61K 39/395, G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP13726537

PYRAZOLOPYRIMIDONE AND PYRAZOLOPYRIDONE INHIBITORS OF TANKYRASE

IPC classification:
A61K 31/437, A61K 31/519, A61P 35/00, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13729367

PYRROLOPYRAZONE INHIBITORS OF TANKYRASE

IPC classification:
A61K 31/495, A61K 31/4985, A61P 35/00, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13730887

DIFLUORO-HEXAHYDRO-CYCLOPENTAOXAZINYLS AND DIFLUORO-HEXAHYDRO-BENZOOXAZINYLS AS BACE1 INHIBITORS

IPC classification:
A61K 31/536, A61P 25/00, C07D 265/12, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13729366

PYRANOPYRIDONE INHIBITORS OF TANKYRASE

IPC classification:
C07D 491/052, C07D 491/147, C07D 491/153, C07D 495/14
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13736570

ANTIPROLIFERATIVE BENZO [B]AZEPIN- 2 - ONES

IPC classification:
A61K 31/55, A61P 35/00, C07D 223/16, C07D 401/06, C07D 403/06, C07D 403/10, C07D 403/12, C07D 405/10, C07D 405/12, C07D 409/06, C07D 413/06, C07D 413/10, C07D 417/06, C07D 417/10, C07D 471/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP13747659

SUBSTITUTED HETERO-AZEPINONES

IPC classification:
A61K 31/553, A61K 31/554, C07D 267/14, C07D 281/10, C07D 498/10
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13745838

AZAHETEROCYCLES AS BIR2 AND/OR BIR3 INHIBITORS

IPC classification:
A61K 31/40, A61K 31/47, C07D 209/44, C07D 217/26, C07D 401/12, C07D 405/06, C07D 409/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP13766920

2-OXO-2,3,4,5-TETRAHYDRO-1 H-BENZO[B]DIAZEPINES AND THEIR USE IN THE TREATMENT OF CANCER

IPC classification:
A61K 31/5513, A61P 35/00, C07K 5/062
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP13774407

AZAINDOLINES

IPC classification:
A61K 31/437, A61P 35/00, C07D 471/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP13773766

AZAINDOLINES

IPC classification:
A61K 31/437, A61P 35/00, C07D 471/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP13771145

INDOLINES

IPC classification:
A61K 31/404, A61P 35/00, C07D 209/42
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP11718393

HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES

IPC classification:
A61K 31/5517, A61P 1/16, A61P 9/00, A61P 9/04, A61P 9/12, A61P 15/10, A61P 25/00, A61P 25/18, A61P 25/22, A61P 25/24, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP13782683

MGLU2/3 ANTAGONISTS FOR THE TREATMENT OF AUTISTIC DISORDERS

IPC classification:
A61K 9/00, A61K 31/00, A61K 31/444, A61K 31/519, A61P 25/00, A61P 25/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
GRANT OF PATENT INTENDED
EP13802359

DIMERIC COMPOUNDS

IPC classification:
A61K 31/551, A61P 35/00, C07D 243/12, C07D 401/14, C07D 403/12, C07D 403/14
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP14702209

3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS

IPC classification:
A61K 31/4439, A61P 25/16, A61P 25/28, C07D 401/14, C07D 405/04, C07D 405/14, C07D 471/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP14700493

FLUORO-[1,3]OXAZINES AS BACE1 INHIBITORS

IPC classification:
A61K 31/5355, A61P 25/28, C07D 413/10, C07D 413/12, C07D 413/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP14724824

PREDICTING RESPONSE TO EGFR INHIBITORS

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP11720065

2,5,6,7-TETRAHYDRO-[1,4]OXAZEPIN-3-YLAMINE OR 2,3,6,7-TETRAHYDRO-[1,4]OXAZEPIN-5-YLAMINE COMPOUNDS

IPC classification:
A61K 31/553, A61P 25/28, C07D 267/10, C07D 413/12, C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14715908

BACE1 INHIBITORS

IPC classification:
A61K 31/5355, A61P 25/28, A61P 29/00, A61P 35/00, C07D 413/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP14722588

SYNTHESIS OF BACE INHIBITORS

IPC classification:
C07D 213/79, C07D 213/803, C07D 213/85, C07D 241/24, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP14720956

C-LINKED HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINES AND THEIR USES

IPC classification:
A61K 31/506, A61P 25/16, A61P 25/28, C07D 401/14, C07D 403/14, C07D 405/14, C07D 471/04, C07D 493/08
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP14791795

BIHETEROARYL COMPOUNDS AND USES THEREOF

IPC classification:
A61K 31/444, A61K 31/506, A61P 25/00, A61P 25/14, A61P 25/16, A61P 25/18, A61P 25/28, C07D 401/14, C07D 403/14
Applicant:
F. Hoffmann-La Roche SA
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP11711074

ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES

IPC classification:
A61K 31/5517, A61P 15/12, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11748683

BACE INHIBITORS FOR USE IN THE TREATMENT OF DIABETES

IPC classification:
A61K 31/381, A61K 31/40, A61K 31/4155, A61K 31/422, A61K 31/4245, A61K 31/427, A61K 31/4418, A61P 3/10, C07D 207/00, C07D 207/10, C07D 213/16, C07D 231/14, C07D 233/26, C07D 263/34, C07D 275/02
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION REFUSED
EP11724168

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/52, C07D 403/14, C07D 473/16
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11714564

HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS

IPC classification:
A61K 31/5517, A61P 5/24, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14750486

V1A ANTAGONISTS TO TREAT PHASE SHIFT SLEEP DISORDERS

IPC classification:
A61K 31/5517, A61P 25/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP11768005

ILK GENE AS MARKER FOR ERLOTINIB TREATMENT

IPC classification:
C07D 239/94, G01N 33/50, G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP12703325

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/553, A61P 25/00, C07D 267/10, C07D 413/12, C07D 417/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12701922

N-[3-(5-AMINO-3,3A,7,7A-TETRAHYDRO-1H-2,4-DIOXA-6-AZA-INDEN-7-YL)-PHENYL]-AMIDES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/5365, A61P 25/28, C07D 498/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
PATENT GRANTED
EP14789286

CRYSTALLINE FORMS OF A PYRROLIDONE DERIVATIVE USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE AND PREPARATION THEREOF

IPC classification:
C07D 207/273
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP11739092

1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS

IPC classification:
A61K 31/513, A61P 3/10, C07D 239/22, C07D 239/70, C07D 403/12, C07D 405/12, C07D 409/12, C07D 413/12, C07D 417/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11715545

HETEROBIARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES

IPC classification:
A61K 31/5517, A61P 1/16, A61P 9/04, A61P 9/12, A61P 13/12, A61P 15/10, A61P 25/00, A61P 25/18, A61P 25/22, A61P 25/24, C07D 487/04, C07D 519/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14800010

TETRAHYDRO-BENZODIAZEPINONES

IPC classification:
A61K 31/551, A61P 35/00, C07D 243/12, C07D 401/06, C07D 401/14, C07D 403/06, C07D 403/12, C07D 405/06, C07D 405/14, C07D 413/06, C07D 417/12, C07D 487/08
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP12700341

1,4 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

IPC classification:
A61K 31/5375, A61K 31/5377, A61P 3/10, C07D 265/30, C07D 413/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Siena Biotech Spa
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP16155153

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

IPC classification:
A61K 31/52, C07D 403/14, C07D 473/16
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Genentech, Inc.
Agent:
Sam Rogerson Bailey, Mewburn Ellis LLP
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP14805290

SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF

IPC classification:
A61K 31/5517, A61P 25/00, C07D 487/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP14821614

PYRAZOLE DERIVATIVES AND USES THEREOF AS INHIBITORS OF DLK

IPC classification:
A61K 31/4439, A61P 25/00, C07D 401/04, C07D 401/14, C07D 405/14, C07D 413/14, C07D 471/04, C07D 487/04, C07D 491/08, C07D 491/107, C07D 498/04, C07D 498/10
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP14815318

SPIRO-OXAZOLONES

IPC classification:
A61K 31/438, A61P 25/00, C07D 491/10, C07D 491/12, C07D 498/10
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP14821587

5-ARYL-1-IMINO-1-OXO-[1,2,4]THIADIAZINES

IPC classification:
A61K 31/549, A61K 31/554, A61P 25/28, C07D 513/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP15702398

FLUORO-NAPHTHYL DERIVATIVES

IPC classification:
C07D 213/56, C07D 213/61, C07D 309/14, C07D 401/04, C07D 405/12, C07D 405/14
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP15706198

SPIRO-OXAZOLONES

IPC classification:
A61K 31/443, C07D 491/107, C07D 491/20
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION IN PROGRESS
EP15711118

PIPERIDINE-DIONE DERIVATIVES

IPC classification:
A61K 31/4453, A61K 31/4545, A61P 35/00, C07D 401/04, C07D 401/14, C07D 409/04, C07D 409/14, C07D 417/04, C07D 417/14, C07D 487/08, C07D 491/048, C07D 491/08, C07D 491/107
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP15741532

PYRIDYL-TRIAZABICYCLES

IPC classification:
A61K 31/549, A61P 25/00, C07D 417/04, C07D 513/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP15748252

2,2,2-TRIFLUOROETHYL-THIADIAZINES

IPC classification:
A61K 31/54, A61K 45/06, C07D 403/12
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
EXAMINATION REQUESTED
EP15775694

BACE1 INHIBITORS

IPC classification:
A61K 31/542, A61K 31/554, A61P 25/28, C07D 513/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
Request for examination was made
EP15787212

BACE1 INHIBITORS

IPC classification:
A61K 31/542, A61P 25/28, C07D 513/04
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
Request for examination was made
EP15791654

SPIRO-THIAZOLONES

IPC classification:
A61K 31/438, A61P 25/00, C07D 491/107, C07D 491/20
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
Request for examination was made
EP15800821

PEPTIDES

IPC classification:
C07K 7/08
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
Request for examination was made
EP15800822

PEPTIDES

IPC classification:
C07K 7/08
Applicant:
F. Hoffmann-La Roche AG
Agent:
Simona Müller-Afraz, F. Hoffmann-La Roche AG
Status:
Request for examination was made

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