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Alexander Burger has worked on the following 256 EPO patent applications which have been published in the last five years:

EP11723276

ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF

IPC classification:
A61K 39/395, A61P 35/00, A61P 35/04, C07K 16/28, C12N 15/13
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11706266

ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF

IPC classification:
A61P 35/00, A61P 37/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11707416

METHOD FOR PURIFYING IMMUNOGLOBULIN SOLUTIONS

IPC classification:
C07K 1/30, C07K 16/18
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11711071

BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG-2 ANTIBODIES

IPC classification:
C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11710515

SYSTEM AND METHOD TO CORRECT OUT OF PHASE ERRORS IN DNA SEQUENCING DATA BY USE OF A RECURSIVE ALGORITHM

IPC classification:
C12Q 1/68, G06F 19/24
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11719396

TWO-COLOR CHROMOGENIC IN SITU HYBRIDIZATION

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11716402

COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A MTOR INHIBITOR

IPC classification:
A61K 31/00, A61K 39/395
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11720110

RELEASE REAGENT FOR VITAMIN D COMPOUNDS

IPC classification:
G01N 33/82
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11722402

SINGLE B-CELL CULTIVATION METHOD

IPC classification:
G01N 33/50
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP11743838

COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH AN ANTI-VEGF ANTIBODY

IPC classification:
A61K 39/395, C07K 16/22, C07K 16/28
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11746259

BISPECIFIC ANTIBODIES COMPRISING A DISULFIDE STABILIZED - FV FRAGMENT

IPC classification:
C07K 16/00, C07K 16/28, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11746571

ACTIVATABLE BISPECIFIC ANTIBODIES

IPC classification:
C07K 16/00, C07K 16/28, C07K 16/32
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12169177

Dialysis fermenter - biorector with dialysis device

IPC classification:
C12M 3/06
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION WITHDRAWN
EP11743069

ANTI-HUMAN IGG1 ANTIBODY

IPC classification:
C07K 16/42, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11766965

ANTIBODIES AGAINST HUMAN TWEAK AND USES THEREOF

IPC classification:
C07K 16/24
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11778868

OPTIMIZED METHOD FOR ANTIBODY CAPTURING BY MIXED MODE CHROMATOGRAPHY

IPC classification:
C07K 16/06, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The patent has been granted
EP11802941

POLYPEPTIDE-POLYNUCLEOTIDE-COMPLEX AND ITS USE IN TARGETED EFFECTOR MOIETY DELIVERY

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/00, C07K 16/18, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11790633

FEED MIXING DEVICE AND ITS USE

IPC classification:
C12N 5/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11804712

A PHARMACEUTICAL COMPOSITION OF A COMPLEX OF AN ANTI-DIG ANTIBODY AND DIGOXIGENIN THAT IS CONJUGATED TO A PEPTIDE

IPC classification:
A61K 39/385, A61K 39/395, A61K 47/48, A61P 3/00, A61P 35/00, A61P 43/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12701289

HEMATOXYLIN STAINING METHOD

IPC classification:
G01N 1/30, G01N 1/31
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12703740

CHROMATOGRAPHY COLUMN SUPPORT

IPC classification:
G01N 30/56, G01N 30/60
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP12702549

NEW IRIDIUM-BASED COMPLEXES FOR ECL

IPC classification:
C07F 15/00, C12Q 1/68, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The patent has been granted
EP12702046

NEW IRIDIUM-BASED COMPLEXES FOR ECL

IPC classification:
C07F 15/00, C12Q 1/68, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The patent has been granted
EP12191535

Protein expression from multiple nucleic acids

IPC classification:
C07K 16/00, C12N 15/69, C12N 15/85
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12170648

Protein expression from multiple nucleic acids

IPC classification:
C07K 16/00, C12N 15/69, C12N 15/85
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12706226

METHOD FOR TISSUE SAMPLE FIXATION

IPC classification:
G01N 1/30
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12704831

ANTIBODIES AGAINST HUMAN IL33R AND USES THEREOF

IPC classification:
A61K 39/395, A61P 11/06, A61P 19/02, A61P 37/06, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12749229

PRESENCE OF ERG GENE REARRANGEMENTS AND PROTEIN OVER-EXPRESSION IN LOW GRADE PIN (LG-PIN) IN PROSTATE BIOPSIES

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12708515

MONOVALENT ANTIGEN BINDING PROTEINS

IPC classification:
C07K 16/00, C07K 16/18, C07K 16/30
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12706242

ANTIGEN BINDING PROTEINS

IPC classification:
C07K 16/00, C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12709822

APPLICATION OF QUANTUM DOTS FOR NUCLEAR STAINING

IPC classification:
B82Y 15/00, C12Q 1/68, G01N 33/533, G01N 33/58
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP13153217

Antibodies against human TWEAK and uses thereof

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12708006

NNMT AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12707587

FEN1 AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12707586

APEX1 AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12707316

ASC AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12707315

ARMET AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12707313

SEPRASE AS MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12708546

ION EXCHANGE CHROMATOGRAPHY WITH IMPROVED SELECTIVITY FOR THE SEPARATION OF POLYPEPTIDE MONOMERS, AGGREGATES AND FRAGMENTS BY MODULATION OF THE MOBILE PHASE

IPC classification:
C07K 1/18, C07K 16/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12713624

METHODS FOR SYNTHESIS OF AN OLIGOPEPTIDE MICROARRAY

IPC classification:
C07K 17/06
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12708140

A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12710732

ANTIBODY FC VARIANTS

IPC classification:
C07K 16/28
Applicant:
Roche Glycart AG
Agent:
Seán Malcolm Walton, Mewburn Ellis LLP
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12713128

DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS

IPC classification:
C07H 19/02, C07K 2/00
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12714707

METHOD AND CONSTRUCTS FOR THE PH DEPENDENT PASSAGE OF THE BLOOD-BRAIN-BARRIER

IPC classification:
C07K 16/28
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12717787

AN ANTIBODY SPECIFICALLY BINDING TO INSULIN-LIKE GROWTH FACTOR-1

IPC classification:
C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12720476

AMINO ACID SEQUENCE PRESENTING FUSION POLYPEPTIDE AND ITS USE

IPC classification:
C07K 14/195, C07K 14/415, C07K 14/47, C07K 16/22, C12N 9/90
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12701078

HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Barbara Herren, Roche Diagnostics International AG
Agent:
Multiple attorneys, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11763704

METHOD FOR CELL LYSIS AND PCR WITHIN THE SAME REACTION VESSEL

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Patrick Merkel, Roche Diagnostics International AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11763931

METHOD FOR CELL LYSIS IN A PCR REACTION BUFFER

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Patrick Merkel, Roche Diagnostics International AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12728475

ANTI-HUMAN EPO RECEPTOR ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12728091

REMOVAL OF TARGET CELLS BY CIRCULATING VIRUS-SPECIFIC CYTOTOXIC T-CELLS USING MHC CLASS I COMPRISING COMPLEXES

IPC classification:
A61K 47/48, C07K 14/705, C07K 16/28, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12733052

METHOD FOR SEPARATION OF MONOMERIC POLYPEPTIDES FROM AGGREGATED POLYPEPTIDES

IPC classification:
C07K 1/18, C07K 1/20, C07K 1/36, C07K 14/54, C07K 19/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11767992

SYSTEM AND METHOD FOR DETECTION OF HIV-1 CLADES AND RECOMBINANTS OF THE REVERSE TRANSCRIPTASE AND PROTEASE REGIONS

IPC classification:
C12Q 1/70
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11763644

SYSTEM AND METHOD FOR PRODUCING FUNCTIONALLY DISTINCT NUCLEIC ACID LIBRARY ENDS THROUGH USE OF DEOXYINOSINE

IPC classification:
C12N 15/66
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12748504

SHORTENED TETRANECTIN-APOLIPOPROTEIN A-I FUSION PROTEIN, A LIPID PARTICLE CONTAINING IT, AND USES THEREOF

IPC classification:
C07K 14/775
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12748689

CATION AND ANION EXCHANGE CHROMATOGRAPHY METHOD

IPC classification:
C07K 1/18
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12759484

METHOD FOR OBTAINING FAB FRAGMENTS FROM SINGLE ANTIBODY PRODUCING CELLS BY MULTIPLEXED PCR IN COMBINATION WITH TaqMan PROBES

IPC classification:
C07K 16/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12759454

CO2 PROFILE CULTIVATION

IPC classification:
C07K 14/435, C12N 15/85, C12P 21/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12759148

BISPECIFIC ANTI-EGFR/ANTI IGF-1R ANTIBODIES

IPC classification:
C07K 16/28
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13158348

Improved sequence tags

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12783981

PREPARATIVE COLUMN CHROMATOGRAPHY SYSTEM

IPC classification:
B01D 19/00, G01N 30/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12784604

RELEASE REAGENT FOR VITAMIN D COMPOUNDS

IPC classification:
G01N 33/82
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14152732

Bispecific anti-VEGF/anti-ANG-2 antibodies

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/22, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12788221

CD40L EXPRESSING MAMMALIAN CELLS AND THEIR USE

IPC classification:
C07K 16/00, C12N 5/0781, C12N 5/16
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP12182651

Microfluidic chip, device and system for the generation of aqueous droplets in emulsion oil for nucleic acid amplification

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Barbara Herren, Roche Diagnostics International AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12798775

ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF

IPC classification:
C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP14152731

Bispecific anti-VEGF/anti-ANG-2 antibodies

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/22, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12813822

EXPRESSION VECTOR ORGANIZATION, NOVEL PRODUCTION CELL GENERATION METHODS AND THEIR USE FOR THE RECOMBINANT PRODUCTION OF POLYPEPTIDES

IPC classification:
C12N 15/09, C12N 15/85, C12N 15/87
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12812945

RAPID METHOD FOR CLONING AND EXPRESSION OF COGNATE ANTIBODY VARIABLE REGION GENE SEGMENTS

IPC classification:
C07K 16/00, C12N 15/10, C12N 15/63
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12808373

FULL LENGTH ANTIBODY DISPLAY SYSTEM FOR EUKARYOTIC CELLS AND ITS USE

IPC classification:
C07K 16/26, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13197845

Bispecific antigen binding proteins

IPC classification:
C07K 16/22, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP14170386

Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12712998

SYSTEM AND METHOD FOR DETECTION OF HIV INTEGRASE VARIANTS

IPC classification:
C12Q 1/70
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12711122

WHOLE PROTEOME TILING MICROARRAYS

IPC classification:
C07K 1/04, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12816215

AUTOMATED ANALYSIS OF CIRCULATING TUMOR CELLS

IPC classification:
C12Q 1/68, G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11732485

METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER THERAPY

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13701057

DEVICES AND METHODS FOR DETECTING BIO-ANALYTES USING OPTICALLY DECIPHERABLE PATTERNS

IPC classification:
C07K 1/04, C12Q 1/68, G01N 33/543
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13700576

POLYMER STABILIZATION OF CHROMOGEN SOLUTIONS

IPC classification:
C12Q 1/28, G01N 33/532, G01N 33/535
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13701628

METHOD FOR THE DETECTION OF A BINDING PARTNER OF A MULTISPECIFIC BINDER

IPC classification:
G01N 33/543
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13704599

FC-RECEPTOR BASED AFFINITY CHROMATOGRAPHY

IPC classification:
B01D 15/38, C07K 1/22, C07K 16/06
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13705764

SYSTEM AND METHOD FOR GENERATION AND USE OF COMPACT CLONALLY AMPLIFIED PRODUCTS

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13707142

METHOD FOR REDUCTION OF 1->2 READING FRAME SHIFTS

IPC classification:
C07K 14/775, C12N 15/67
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13706269

ON-COLUMN ENZYMATIC CLEAVAGE

IPC classification:
C07K 1/22, C07K 14/47, C07K 14/775, C07K 17/06
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13705814

METHOD FOR REDUCTION OF 1->3 READING FRAME SHIFTS

IPC classification:
C07K 14/775, C12N 15/67
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14187243

Whole proteome tiling microarrays

IPC classification:
C07K 1/04, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13707879

MULTIPLEXED CHROMATOGRAPHY-IMMUNOASSAY METHOD FOR THE CHARACTERIZATION OF CIRCULATING IMMUNE COMPLEXES

IPC classification:
G01N 33/564, G01N 33/68, G01N 33/94
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13708156

COMBINATION THERAPY OF ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF

IPC classification:
A61K 39/395, A61K 45/06, A61K 47/48, A61P 35/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP14183971

Antibody specifically binding to digoxigenin

IPC classification:
A61K 31/704, A61K 39/00, A61K 39/395, A61K 47/48, B82Y 5/00, C07K 16/16, C07K 16/28, C07K 16/32, C07K 16/44, C07K 16/46, C12N 15/11, C12N 15/113
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP14188054

Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14187233

Whole proteome tiling microarrays

IPC classification:
C07K 1/04, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION REFUSED
EP13175349

N-terminally truncated glycosyltransferases

IPC classification:
C12N 9/10
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION WITHDRAWN
EP11738740

ANTI-MHC ANTIBODY ANTI-VIRAL CYTOKINE FUSION PROTEIN

IPC classification:
A61K 47/48, C07K 16/08, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13705765

GRAM STAINING METHOD WITH IMPROVED DECOLORIZATION OF THE CRYSTAL VIOLET-IODINE COMPLEX FROM GRAM NEGATIVE BACTERIA

IPC classification:
C12Q 1/04
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13179034

Method for improving the recombinant expression of a polypeptide by C-terminal fusion to human neprilysin

IPC classification:
C12N 9/64, C12N 15/67, C12N 15/85
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13714818

SIGNALING CONJUGATES AND METHODS OF USE

IPC classification:
G01N 33/542
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13716242

BISPECIFIC ANTIBODIES AGAINST HUMAN TWEAK AND HUMAN IL17 AND USES THEREOF

IPC classification:
A61K 39/395, C07K 16/24, C07K 16/28, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13718536

METHOD FOR THE EXPRESSION OF POLYPEPTIDES USING MODIFIED NUCLEIC ACIDS

IPC classification:
C12N 15/67
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP14181036

System and method for nucleic acid amplification

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12769409

PROCESS FOR ANTIBODY G1 GLYCOFORM PRODUCTION

IPC classification:
C07K 16/00, C07K 16/28, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14188057

Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP14180909

System and method for automated nucleic acid amplification

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14188048

Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11735862

METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER THERAPY

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11732484

METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER THERAPY

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11743988

METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER THERAPY

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP11719506

SYSTEM AND METHOD FOR PURIFICATION AND USE OF INORGANIC PYROPHOSPHATASE FROM AQUIFEX AEOLICUS

IPC classification:
C12N 9/14
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13724269

MULTISPECIFIC ANTIBODIES

IPC classification:
A61K 39/395, C07K 16/22, C07K 16/28, C07K 16/32, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11732486

METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER THERAPY

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP14188047

Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy

IPC classification:
G01N 33/574
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13155433

Combination therapy of a type II anti-CD20 antibody with an anti-Bcl-2 active agent

IPC classification:
A61K 39/395, A61P 35/00
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13730906

METHOD FOR SELECTION AND PRODUCTION OF TAILOR-MADE HIGHLY SELECTIVE AND MULTI-SPECIFIC TARGETING ENTITIES CONTAINING AT LEAST TWO DIFFERENT BINDING ENTITIES AND USES THEREOF

IPC classification:
C07K 16/00, C07K 16/46, C12N 9/16, C12N 9/52, C12N 9/80, C12P 21/06
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13734693

METHOD FOR THE SELECTION AND PRODUCTION OF TAILOR-MADE, SELECTIVE AND MULTI-SPECIFIC THERAPEUTIC MOLECULES COMPRISING AT LEAST TWO DIFFERENT TARGETING ENTITIES AND USES THEREOF

IPC classification:
A61K 39/395, C07K 16/00, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13731144

METHOD FOR MAKING ANTIBODY FC-REGION CONJUGATES COMPRISING AT LEAST ONE BINDING ENTITY THAT SPECIFICALLY BINDS TO A TARGET AND USES THEREOF

IPC classification:
C07K 16/00, C12N 9/64
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13737565

COVALENTLY LINKED ANTIGEN-ANTIBODY CONJUGATES

IPC classification:
A61K 39/395, A61K 47/48, C07K 16/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13737564

ANTI-THEOPHYLLINE ANTIBODIES AND METHODS OF USE

IPC classification:
A61K 39/00, C07K 16/44
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13734999

ANTI-BIOTIN ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/44
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13734747

RECOMBINANTLY PRODUCED NEUTRAL PROTEASE ORIGINATING FROM PAENIBACILLUS POLYMYXA

IPC classification:
C07K 14/435
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP13736565

BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES AND THEIR USE IN THE TREATMENT OF OCULAR VASCULAR DISEASES

IPC classification:
C07K 16/22, C07K 16/28, C07K 16/46
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13735290

METHOD FOR THE DETECTION OF A MULTISPECIFIC BINDER

IPC classification:
G01N 33/543, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13193588

New compound for sequencing by synthesis

IPC classification:
C07H 19/06, C07H 19/16, C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13750004

METHOD FOR PRODUCING SOLUBLE FcR AS Fc-FUSION WITH INERT IMMUNOGLOBULIN Fc-REGION AND USES THEREOF

IPC classification:
C12N 15/79
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13744530

METHOD FOR PRODUCING MONOMERIC AND MULTIMERIC MOLECULES AND USES THEREOF

IPC classification:
C12N 15/79
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13745066

IMMUNOASSAY-BASED DETERMINATION OF IN-SOLUTION BINDING KINETICS

IPC classification:
G01N 33/557
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13763039

METHOD FOR THE PRODUCTION OF POLYPEPTIDES IN THE PERIPLASM OF PROKARYOTIC CELLS

IPC classification:
C07K 1/14, C12P 21/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13759782

METHOD FOR THE PRODUCTION AND SELECTION OF MOLECULES COMPRISING AT LEAST TWO DIFFERENT ENTITIES AND USES THEREOF

IPC classification:
C07K 1/107
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The patent has been granted
EP13712120

METHOD OF IDENTIFYING TREATMENT RESPONSIVE NON-SMALL CELL LUNG CANCER USING ANAPLASTIC LYMPHOMA KINASE (ALK) AS A MARKER

IPC classification:
G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The patent has been granted
EP12180072

Improved method for amplification of target nucleic acids using a multi-primer approach

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13773733

METHODS, KITS, AND SYSTEMS FOR CLARIFYING PIGMENTED SAMPLES

IPC classification:
G01N 1/30
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP12181231

A conjugate of an antibody against CD4 and antifusogenic peptides

IPC classification:
A61K 47/48, A61P 31/12, C07K 14/16
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP13766980

PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS

IPC classification:
C07F 9/24, C07F 9/6561, C07H 19/00
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13789759

ANTI-HER3/HER4 ANTIGEN BINDING PROTEINS BINDING TO THE BETA-HAIRPIN OF HER3 AND THE BETA-HAIRPIN OF HER4

IPC classification:
A61K 39/00, A61K 39/395, A61P 35/00, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13811131

HER3 ANTIGEN BINDING PROTEINS BINDING TO THE BETA-HAIRPIN OF HER3

IPC classification:
A61K 47/48, C07K 14/195, C07K 14/705, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12784580

NUCLEIC ACIDS ENCODING CHIMERIC POLYPEPTIDES FOR LIBRARY SCREENING

IPC classification:
C12N 15/10, C40B 40/06
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP13795771

REMOVAL OF CANCER CELLS BY CIRCULATING VIRUS-SPECIFIC CYTOTOXIC T-CELLS USING CANCER CELL TARGETED MHC CLASS I COMPRISING MULTI-FUNCTION PROTEINS

IPC classification:
A61K 47/00, C07K 14/045, C07K 14/74, C07K 16/28, C07K 16/30, C07K 16/46
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP13808036

DISULFIDE-LINKED MULTIVALENT MHC CLASS I COMPRISING MULTI-FUNCTION PROTEINS

IPC classification:
C07K 14/705, C07K 14/74, C07K 16/28, C07K 16/30, C07K 19/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP15168902

ANTIBODIES BINDING PREFERENTIALLY HUMAN CSF1R EXTRACELLULAR DOMAIN 4 AND THEIR USE

IPC classification:
A61K 39/00, A61P 35/00, A61P 37/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11748041

CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP14706005

USE OF AN AMINO ACID AUXOTROPHY CURED PROKARYOTIC STRAIN FOR THE RECOMBINANT PRODUCTION OF A POLYPEPTIDE

IPC classification:
C12P 21/02
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP15176208

METHOD TO SCREEN HIGH AFFINITY ANTIBODY

IPC classification:
C07K 16/26, G01N 21/55, G01N 21/552, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14708893

PROXIMITY ASSAY FOR IN SITU DETECTION OF TARGETS

IPC classification:
C12Q 1/25, G01N 33/535, G01N 33/58
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14711244

SPECIFIC DETECTION OF RAT ANTIBODIES IN MOUSE SERUM

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14718115

COMBINATION THERAPY OF ANTIBODIES AGAINST HUMAN CSF-1R AND TLR9 AGONIST

IPC classification:
A61K 39/395, A61K 45/06, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14721806

HUMAN FCRN-BINDING MODIFIED ANTIBODIES AND METHODS OF USE

IPC classification:
A61K 39/395, A61P 27/02, C07K 16/22, C07K 16/28, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14721295

FCRN-BINDING ABOLISHED ANTI-IGF-1R ANTIBODIES AND THEIR USE IN THE TREATMENT OF VASCULAR EYE DISEASES

IPC classification:
C07K 16/22, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP12700573

METHOD AND SUBSTANCES FOR PREPARATION OF N-SUBSTITUTED PYRIDINIUM COMPOUNDS

IPC classification:
C07D 213/46
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14722660

NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF MIXTURES BY DEEP SEQUENCING OF HLA GENE AMPLICONS USING NEXT GENERATION SYSTEMS

IPC classification:
C12Q 1/68
Applicant:
The Scripps Research Institute
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14725130

QUANTITATIVE CONTROL OF SIALYLATION

IPC classification:
A61K 39/395, C12P 19/18, C12P 21/00
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11799415

COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A MDM2 INHIBITOR

IPC classification:
A61P 35/00, C07K 16/28
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP12185993

Stabilization of thermolysin in aqueous solution

IPC classification:
C12N 9/54, C12N 9/96
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11774051

USE OF SIGNAL ENHANCING COMPOUNDS IN ELECTROCHEMILUMINESCENCE DETECTION

IPC classification:
G01N 21/66, G01N 21/76
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14736379

PROCESS FOR THE MONO- AND BI-SIALYLATION OF GLYCOPROTEINS EMPLOYING N-TERMINALLY TRUNCATED BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE MUTANTS

IPC classification:
C07K 16/00, C12N 9/10, C12P 19/18, C12P 21/00
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP14744107

COMPOSITIONS AND METHODS FOR BISULFITE CONVERTED SEQUENCE CAPTURE

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP14744841

METHOD FOR THE RECOMBINANT PRODUCTION OF A POLYPEPTIDE IN PROKARYOTIC CELLS

IPC classification:
C12N 9/02, C12N 15/52, C12R 1/19
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP14745144

SEQUENCE CAPTURE METHOD USING SPECIALIZED CAPTURE PROBES (HEATSEQ)

IPC classification:
C12Q 1/28
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11711313

BISPECIFIC ANTIBODIES

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/22, C07K 16/28, C07K 16/46
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP11717976

METHOD FOR MEASUREMENT OF CALCIUM IONS

IPC classification:
C07C 229/18, G01N 33/84
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11721748

HYDROPHOBIC INTERACTION CHROMATOGRAPHY METHOD

IPC classification:
C07K 14/435, G01N 30/02
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14199625

Sialyltransferase without CMP-dependent sialidase activity

IPC classification:
C12N 9/10, C12P 19/44
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION REFUSED
EP11715213

Immunoglobulin aggregate removal

IPC classification:
C07K 1/20, C07K 1/32, C07K 16/06
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP14758893

METHOD FOR IMPROVING ANTIBODY STABILITY

IPC classification:
G01N 33/68, G06F 19/16
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11754693

METHOD FOR PURIFYING PEGYLATED ERYTHROPOIETIN

IPC classification:
A61K 47/48, B01D 15/36
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14761904

COMBINATION THERAPY OF ANTIBODIES AGAINST HUMAN CSF-1R AND ANTIBODIES AGAINST HUMAN PD-L1

IPC classification:
A61K 39/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11802372

ISOFORM ENRICHED ANTIBODY PREPARATION AND METHOD FOR OBTAINING IT

IPC classification:
C07K 16/00, C07K 16/18, C07K 16/30, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP14772115

THERMUS THERMOPHILUS SLYD FKBP DOMAIN SPECIFIC ANTIBODIES

IPC classification:
C07K 16/12
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
GRANT OF PATENT INTENDED
EP11813853

ENHANCED DEPOSITION OF CHROMOGENS UTILIZING PYRIMIDINE ANALOGS

IPC classification:
C12Q 1/68, G01N 33/52, G01N 33/531, G01N 33/58
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP15155059

Method of assessing rheumatoid arthritis by measuring anti-CCP and anti-Casp8

IPC classification:
G01N 33/564
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION WITHDRAWN
EP15155063

Method of assessing rheumatoid arthritis by measuring anti-CCP and anti-MCM3

IPC classification:
G01N 33/564
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION WITHDRAWN
EP14781237

MULTISPECIFIC DOMAIN EXCHANGED COMMON VARIABLE LIGHT CHAIN ANTIBODIES

IPC classification:
C07K 16/28, C07K 16/40
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION IN PROGRESS
EP11751996

SUBSTRATES FOR CHROMOGENIC DETECTION AND METHODS OF USE IN DETECTION ASSAYS AND KITS

IPC classification:
C07F 9/6503
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP12196714

Distinguishing assay

IPC classification:
G01N 33/576, G01N 33/68, G01N 33/94
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11778872

SPECTROSCOPIC FINGER-PRINTING OF RAW MATERIAL

IPC classification:
G01N 21/35, G01N 21/64
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11773415

A CONJUGATE BETWEEN A THIOPHILIC SOLID PHASE AND AN OLIGONUCLEOTIDE COMPRISING A THIOOXONUCLEOTIDE

IPC classification:
C07H 21/02, C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11801732

CHROMATOGRAPHY EQUIPMENT CHARACTERIZATION

IPC classification:
C07K 1/16, G01N 30/86, G01N 30/88
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11763703

METHOD FOR CELL LYSIS IN A RT-PCR REACTION BUFFER

IPC classification:
C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Patrick Merkel, Roche Diagnostics International AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP10841723

SIMULTANEOUS DETECTION OF MUTATIONAL STATUS AND GENE COPY NUMBER

IPC classification:
C07H 21/04, G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP10798778

Sequence dependent aggregation

IPC classification:
C07K 16/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11757847

SERPIN-FINGER FUSION POLYPEPTIDE

IPC classification:
C07K 14/16, C07K 14/81, C12N 15/62
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11746230

AN ASSAY FOR MEASUREMENT OF ANTIBODIES BINDING TO A THERAPEUTIC MONOCLONAL ANTIBODY

IPC classification:
C40B 30/04, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11746573

ANTIBODIES AGAINST IL-18R1 AND USES THEREOF

IPC classification:
A61K 39/395, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP11748406

ALKALINE FEED

IPC classification:
C07K 14/775, C12N 1/20, C12P 21/00, C12P 21/02
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14799764

ANTI-alpha-SYNUCLEIN ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/18, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11714284

METHOD FOR THE SELECTION OF A LONG-TERM PRODUCING CELL

IPC classification:
C07K 16/00, C12P 21/02, C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP11748106

IN-SITU HYBRIDIZATION WITH POLYTAG PROBES

IPC classification:
C07H 21/00, C12Q 1/68, G01N 33/48
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP11808627

DETECTION OF A POSTTRANSLATIONALLY MODIFIED POLYPEPTIDE BY A BI-VALENT BINDING AGENT

IPC classification:
G01N 33/50, G01N 33/531
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP14805947

IMPROVED PROCESS FOR PRODUCING MAGNETIC MONODISPERSE POLYMER PARTICLES

IPC classification:
C08F 257/02, H01F 1/00
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14825111

USE OF THE BINDING DOMAIN OF A SUBUNIT OF A MULTI-SUBUNIT STRUCTURE FOR TARGETED DELIVERY OF PHARMACEUTICALLY ACTIVE ENTITIES TO THE MULTI-SUBUNIT STRUCTURE

IPC classification:
A61K 38/55, C07K 14/78, C07K 14/81, C12N 15/62
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14812183

SPR-BASED BRIDGING ASSAY FOR DETERMINING THE BIOLOGICAL ACTIVITY OF MULTIVALENT, MULTISPECIFIC MOLECULES

IPC classification:
G01N 33/543, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14827183

IMPROVED RECOMBINANT POLYPEPTIDE PRODUCTION METHODS

IPC classification:
C12P 21/00, C12P 21/02
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14827191

HUMANIZED ANTI-Tau(pS422) ANTIBODIES AND METHODS OF USE

IPC classification:
A61P 25/28, C07K 14/47, C07K 16/18, C07K 16/30
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14821592

COMBINATION THERAPY WITH AN ANTI-ANG2 ANTIBODY AND A CD40 AGONIST

IPC classification:
A61K 39/00, A61K 39/395, C07K 16/22, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14811848

USE OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXIGENASE (PAM) FOR C-TERMINAL AMIDATION

IPC classification:
C07K 14/435
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP16161377

ENHANCED DEPOSITION OF CHROMOGENS UTILIZING PYRIMIDINE ANALOGS

IPC classification:
C12Q 1/68, G01N 33/52, G01N 33/531, G01N 33/58
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP10794936

Antibodies binding to human CSF1R extracellular domain 4 and their use

IPC classification:
A61P 35/00, A61P 37/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP14821164

ENRICHMENT OF FULL-LENGTH OLIGONUCLEOTIDES VIA TRANSCRIPTION/TRANSLATION-MEDIATED PURIFICATION

IPC classification:
C12N 15/09
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14835556

BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES

IPC classification:
A61K 39/395, A61K 47/48, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14825155

COVALENTLY LINKED POLYPEPTIDE TOXIN-ANTIBODY CONJUGATES

IPC classification:
A61K 47/48, A61P 35/00, C07K 16/44
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14821205

COVALENTLY LINKED HELICAR-ANTI-HELICAR ANTIBODY CONJUGATES AND USES THEREOF

IPC classification:
A61K 47/48, C07K 16/44, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11704217

Method for the determination of sequence variants of polypeptides

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
PATENT GRANTED
EP15700545

FC-REGION VARIANTS WITH IMPROVED PROTEIN A-BINDING

IPC classification:
A61K 39/00, C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15703229

FC-REGION VARIANTS WITH MODIFIED FCRN-BINDING PROPERTIES

IPC classification:
A61K 39/00, C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15700148

FC-REGION VARIANTS WITH MODIFIED FCRN- AND MAINTAINED PROTEIN A-BINDING PROPERTIES

IPC classification:
A61K 39/00, C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14830531

MONOVALENT BLOOD BRAIN BARRIER SHUTTLE MODULES

IPC classification:
C07K 16/18, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15701368

STABILIZATION OF WHOLE BLOOD AT ROOM TEMPERATURE

IPC classification:
A01N 1/02, C09K 15/24
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP12162102

T7 RNA polymerase variants with Cysteine-Serine substitutions

IPC classification:
C12N 9/12, C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP10798541

ANTI-HER3 Antibodies and uses thereof

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/28, C07K 16/32
Applicant:
Roche Glycart AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP15708126

TARGETED SEQUENCING AND UID FILTERING

IPC classification:
C12N 15/10, C12Q 1/68
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11702211

Protein conjugates for trypsin mediated pegylation by transamidation and methods

IPC classification:
A61K 47/48, C07K 1/107, C07K 5/10, C07K 14/65
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP15705997

SINGLE-STRANDED OLIGONUCLEOTIDE PROBES FOR CHROMOSOME OR GENE COPY ENUMERATION

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15173638

ANTIBODIES AGAINST HUMAN CSF-1R FOR USE IN INDUCING LYMPHOCYTOSIS IN LYMPHOMAS OR LEUKEMIAS

IPC classification:
A61K 39/395
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION PUBLISHED
EP10801085

METHODS FOR PRODUCING UNIQUELY SPECIFIC NUCLEIC ACID PROBES

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION DEEMED TO BE WITHDRAWN
EP15705334

AUTOMATED RNA DETECTION USING LABELED 2'-O-METHYL RNA OLIGONUCLEOTIDE PROBES AND SIGNAL AMPLIFICATION SYSTEMS

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15706439

QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION

IPC classification:
C07C 27/00, G01N 33/58
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15706450

METHODS, KITS, AND SYSTEMS FOR SCORING THE IMMUNE RESPONSE TO CANCER BY SIMULTANEOUS DETECTION OF CD3, CD8, CD20 AND FOXP3

IPC classification:
G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP11702212

3D ADCC NK FACS ASSAY

IPC classification:
G01N 33/50
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
NO OPPOSITION FILED WITHIN TIMELIMIT
EP15710178

IN VITRO PREDICTION OF IN VIVO HALF-LIFE OF ANTIBODIES

IPC classification:
B01D 15/38, B01J 20/32, C07K 16/00, C07K 16/24
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15741892

MULTISPECIFIC ANTIBODIES

IPC classification:
C07K 16/22, C07K 16/24, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15712970

METHOD FOR DETECTING MULTISPECIFIC ANTIBODY LIGHT CHAIN MISPAIRING

IPC classification:
C07K 16/22, C07K 16/24, C07K 16/28, C12Q 1/37, G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP16188558

MULTISTEP FINAL FILTRATION

IPC classification:
C07K 16/06, C07K 16/28, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15720937

HEMATOXYLIN PRECIPITATE CLEANING METHOD AND SYSTEM

IPC classification:
B01L 3/00, B01L 9/06, G01N 1/31, G01N 35/10
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP16189277

COVALENTLY LINKED ANTIGEN-ANTIBODY CONJUGATES

IPC classification:
A61K 39/395, C07K 16/00, A61K 47/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP16188547

ANTI-THEOPHYLLINE ANTIBODIES AND METHODS OF USE

IPC classification:
A61K 31/522, A61K 39/00, C07K 16/44
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP16188552

METHOD FOR THE EXPRESSION OF POLYPEPTIDES USING MODIFIED NUCLEIC ACIDS

IPC classification:
C12N 15/67
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15723910

METHOD FOR PRODUCTION OF POLYPEPTIDES

IPC classification:
C12N 15/85
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15722206

METHOD FOR THE SELECTION OF A LONG-TERM PRODUCING CELL USING HISTONE ACYLATION AS MARKERS

IPC classification:
C12N 15/67
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP14728851

METHOD FOR PRODUCING ANTIBODIES USING OVINE B-CELLS AND USES THEREOF

IPC classification:
A61K 38/00, A61K 39/395, C07K 16/28, C12N 5/0781
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15723206

HER3/HER2 BISPECIFIC ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3 AND DOMAIN II OF HER2

IPC classification:
A61P 35/00, C07K 16/32, A61K 47/50
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15721719

ANTI-HER3 ANTIBODIES BINDING TO THE BETA-HAIRPIN OF HER3

IPC classification:
A61K 39/395, A61P 35/00, C07K 16/32, C07K 16/34
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15721718

HER1 ANTIGEN BINDING PROTEINS BINDING TO THE BETA-HAIRPIN OF HER1

IPC classification:
A61K 39/00, C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15188057

TETRAVALENT MULTISPECIFIC ANTIBODIES

IPC classification:
C07K 16/22, C07K 16/28, C07K 16/40, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION PUBLISHED
EP15724692

ANTI-B7-H3 ANTIBODIES AND DIAGNOSTIC USES THEREOF

IPC classification:
C07K 16/28
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15726920

ANTI- INDOLEAMINE 2,3-DIOXYGENASE 1 ANTIBODIES AND DIAGNOSTIC USES THEREOF

IPC classification:
C07K 16/40
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15725002

ANTIBODIES BINDING TO HUMAN AND CYNOMOLGUS CD3 EPSILON

IPC classification:
C07K 16/28
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15188060

MULTISPECIFIC ANTIBODIES

IPC classification:
C07K 16/22, C07K 16/24, C07K 16/28, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION PUBLISHED
EP15725043

PD-L1 ANTIBODIES AND USES THEREOF

IPC classification:
C07K 16/28
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15726647

METHOD FOR SELECTING ANTIBODIES WITH MODIFIED FCRN INTERACTION

IPC classification:
C07K 16/24
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15726957

SIGNIFICANCE OF INTRATUMORAL HER2 HETEROGENEITY IN BREAST CANCER AND USES THEREFORE

IPC classification:
G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15731066

HUMANIZED ANTI-Tau(pS422) ANTIBODY BRAIN SHUTTLES AND USE THEREOF

IPC classification:
A61K 39/395, A61P 25/28, C07K 16/18, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15732216

ANTI-BRDU ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/44
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15747477

SINGLE-STRANDED OLIGONUCLEOTIDE PROBES FOR CHROMOSOME OR GENE COPY ENUMERATION

IPC classification:
C12Q 1/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15744593

METHOD FOR INCREASING THE SPECIFIC PRODUCTION RATE OF EUKARYOTIC CELLS

IPC classification:
C12N 5/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
EXAMINATION REQUESTED
EP15192002

ANTI-TPBG ANTIBODIES AND METHODS OF USE

IPC classification:
A61K 39/00, A61K 49/00, C07K 16/30
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
APPLICATION PUBLISHED
EP15759788

GALACTOENGINEERED IMMUNOGLOBULIN 1 ANTIBODIES

IPC classification:
A61P 35/00, C07K 16/32
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP17155939

METHOD FOR THE PRODUCTION OF A GLYCOSYLATED IMMUNOGLOBULIN

IPC classification:
C07K 16/00
Applicant:
Chugai Pharmaceutical Co., Ltd. (Chugai Seiyaku Kabushiki Kaisha)
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
The application has been published
EP15771573

MULTIPLEX TP53/CEN17/B CELL GENE-PROTEIN CO-DETECTION ASSAY AND UNIQUELY SPECIFIC PROBES FOR 19q12, INSR, ATM, DLEU2, TP53, and 13q12

IPC classification:
C12Q 1/68, G01N 33/574
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15784344

VH-VL-INTERDOMAIN ANGLE BASED ANTIBODY HUMANIZATION

IPC classification:
C07K 16/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15790559

ANTI-TIM3 ANTIBODIES AND METHODS OF USE

IPC classification:
A61P 35/00, C07K 16/28, A61K 47/50
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15784662

METHOD FOR THE DETERMINATION OF ANTI-DRUG ANTIBODIES AGAINST AN EFFECTOR FUNCTION SUPPRESSED HUMAN OR HUMANIZED DRUG ANTIBODY

IPC classification:
G01N 33/68
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15791566

FC-REGION VARIANTS WITH MODIFIED FCRN- AND PROTEIN A-BINDING PROPERTIES

IPC classification:
A61K 39/395, C07K 16/00
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15857563

EXPORTING MEASUREMENTS OF NANOPORE ARRAYS

IPC classification:
G06F 19/22
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15790575

ANTI-ANG2 ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15791586

ANTI-PDGF-B ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15790945

ANTI-IL-1BETA ANTIBODIES AND METHODS OF USE

IPC classification:
C07K 16/22, C07K 16/24
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15790946

BISPECIFIC ANTIBODIES AND METHODS OF USE IN OPHTHALMOLOGY

IPC classification:
C07K 16/22
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15798449

PROXIMITY ASSAYS USING CHEMICAL LIGATION AND HAPTEN TRANSFER

IPC classification:
G01N 33/543, G01N 33/574, G01N 33/68
Applicant:
Ventana Medical Systems, Inc.
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15864120

SELECTABLE VALVE OF A DELIVERY SYSTEM

IPC classification:
B01L 3/00
Applicant:
F. Hoffmann-La Roche AG
Applicant:
Roche Diagnostics GmbH
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made
EP15804386

MULTISPECIFIC ANTIBODIES

IPC classification:
A61K 39/00, C07K 16/28, C07K 16/30, C07K 16/44, C07K 16/46
Applicant:
F. Hoffmann-La Roche AG
Agent:
Alexander Burger, Roche Diagnostics GmbH
Status:
Request for examination was made

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